BAI-2
[brain-specific angiogenesis inhibitor-2] The approved gene symbol is ADGRB2 [Adhesion G protein-coupled receptor B2].
This human gene has been identified by homology to the angiogenesis inhibitor BAI-1 (brain-specific angiogenesis inhibitor-1) (Shiratsuchi et al, 1997). The gene is expressed specifically in brain. The gene maps to human chromosome 1p35.
Kee et al (2002, 2004) have localized expression of BAI-2 to neurons that also express BAI-1 and BAI-3. Kee et al (2002) have demonstrated the existence of alternative splice variants of murine BAI-2, which are defective in parts of type I repeat of thrombospondin
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