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BAD

[BCLxL/BCL2 associated death promoter; BCL2 antagonist of cell death; BCL2-associated agonist of cell death] This protein was identified in a screen aimed at identifying proteins interacting with the anti-apoptotic protein BCL2. The term BCL2L8 [BCL2-like-8] has been used synonymously for BAD. A databank synonym is BBC6 [BCL2-binding component 6].

BAD contains the three BCL2 homology domains BH1, BH2, and BH3 and selectively dimerizes with the two suppressor proteins of apoptosis, ... ... ... ... ... Subscribe to continue reading! ... ...

 

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