B7-1 |
B72 |
Tumor autocrine motility factor |
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a splice variant of murine CD80 that completely lacks the second Ig-like domain coded by exon 3 in activated murine B-cells (Inobe et al, 1996). The variant was known originially as MB7-2 (murine B7-2), which is confusing as B7-2 is another protein, CD86.
Nagamori et al (2002) have reported that B7-1a serves as a more efficacious costimulatory molecule than B7-1 or B7-2 in the induction and maintenance of anti-tumor immune responses against a poorly immunogenic osteosarcoma cell line.
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