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B-lymphoid kinase

[B-lymphoid tyrosine kinase; B-lymphocyte kinase] abbr. BLK (a term with multiple meanings). A cDNA specifying a polypeptide of 55 kDa has been isolated from murine lymphocytes. BLK (on murine chromosome 14; > 30 kb, 13 exons) encodes a protein with tyrosine kinase activity that is related to other src-related protein kinase.

B-lymphoid kinase is expressed specifically in the B-cell lineage. Expression of B-lymphoid kinase is regulated during the development of B-cells: B-lymphoid kinase RNA is expressed in all pro-B-cells, pre-B-cells, and mature B-cell ... ... ... ... ... Subscribe to continue reading! ... ...

 

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