B-cell IgD low B-cells

abbr. BDL B-cells. This subset of B-cells has been identified by Khalil MI et al (2021, 2021). B-cell IgD low B-cell constitute a small subset of splenic B-cells that, in mice, are characterized by the B220(+) CD21(int) CD23(+) CD93(-), intermediate levels of IgM and low or absent cell surface expression of IgD. As shown in a mouse model of experimental autoimmune encephalomyelitis (EAE), the mouse model of multiple sclerosis, the presence of this B-cell subset is required for recovery from autoimmune encephalomyelitis. B-cell IgD low B-cells function as regulatory B-cells ... ... ... ...
 
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Entry last modified: May 2024