Aplysia MIP-related peptides |
Aplysianin E |
Angie |
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Aplysianin A is an antibacterial peptide and anticancer in the albumen gland of the sea hare Aplysia kurodai (Kamiya et al, 1986). The protein is active against Bacillus subtilis and can cause lysis murine MM46 tumor cells. Takamatsu et al (1995) have cloned the cDNA encoding Aplysianin A. Aplysianin A is produced as a precursor protein of 556 amino acid residues with a signal peptide of 19 amino acid residues and contains 6 potential N-glycosylation sites. Aplysianin A shows a 50 % overall amino acid sequence homology to achacin.
For other proteins/peptides with functions in innate immunity and/or antimicrobial activities see also: Innate immunity and defense peptides Dictionary.
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