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Anginex

Mayo et al (1998) have designed a series of synthetic peptide 33mers by incorporating beta-conformation stabilizing residues from the beta-sheet domains of CXC-Chemokines (IL8, PF4) and functionally important residues from the beta-sheet domain of BPI [Bactericidal/permeability-increasing protein], a bactericidal protein of human neutrophils known for its ability to kill bacteria and to neutralize the inflammatory actions of bacterial lipopolysaccharides. These peptides retain the bactericidal activity of the neutrophil bactericidal protein (Mayo et al, 1998).

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