AngFq1
[angiogenesis due to FGF2] Based on the observation that individual mouse strains have dramatically different responses to neovascularization induced by growth factors, Rogers et al (2004) have identified four genetic quantitative trait loci (QTLs) (AngFq1, AngFq2, AngFq3, AngFq4) that influence the extent of angiogenesis (neovascularization) induced by bFGF in mice. Another set of different loci has been identified also for VEGF (Rogers et al, 2003). It is thought that such loci may influence individual susceptibility to diseases such as cancer, macular degeneration, atherosclerosis, and arthritis, all of which are related to
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