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Agglucetin

Agglucetin is a tetrameric C-type lectin-like venom protein from Formosan Agkistrodon acutus (A. acutus) venom (Wang and Huang, 2001). The protein is a platelet glycoprotein Ib binding protein (Wang and Huang, 2001).

Wang (2008) has shown that Agglucetin sustains human umbilical vein endothelial cell proliferation. Agglucetin acts as a survival factor, promotes endothelial adhesion, and angiogenesis by triggering signaling through integrins CD51 and CD61.

See also: Angiogenesis Dictionary section of this encyclopedia for other entries directly bearing on factors and processes involved in the generation of new blood vessels.

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