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This murine gene has been cloned by Gewert et al (1987). Its expression is induced together with IFN-beta in mouse fibroblasts and hamster cell lines by Newcastle Disease virus. Sequence analysis and functional studies show that this gene encodes the murine counterpart of the inhibitor of the metalloproteinase TIMP-1.

For other proteins (or fragments thereof) with at least one additional activity that differs from the established 'classical' activity of the parent protein see also: Dual identity proteins and Cryptides MiniCOPE Dictionary.

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