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2E8

(ATCC TIB-239 2E8) This stromal cell dependent pre-B-cell clone has been described by Ishihara et al (1991). 2E8 have been propagated for more than 1 year in the presence of IL7 alone and is selectively responsive to that cytokine.

2E8 cells depend on IL7 for growth and survival and can be used as an indicator cell line for detecting and quantitating this factor (see also: bioassays, cytokine assays). 2E8 cells respond to human or murine IL7, but the latter has been suggested to be preferable for routine passage and maintenance.

The growth of 2E8 cells in methylcellulose assays (see also: ... ... ... ... ... Subscribe to continue reading! ... ...

 

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